Name: Cheesy Cajun Garlic Chicken Rotini Skillet
Prep time: 15 min
Cook time: 25 min
Total time: 40 min
Yield: 4 servings
Cuisine: American
Ingredients: 2 chicken breasts, diced; 2 cups rotini pasta (dry); 2 tablespoons olive oil; 2 teaspoons Cajun seasoning; 3 cloves garlic, minced; 1 red bell pepper, chopped; ½ cup heavy cream; 1 cup shredded cheddar cheese; ¼ cup grated parmesan cheese; ¼ cup chopped green onions; Salt and black pepper, to taste

Hey y'all! If you're craving a creamy, spicy, and irresistibly cheesy pasta dish, this Cheesy Cajun Garlic Chicken Rotini Skillet will become your new weeknight favorite. It's bursting with savory Cajun flavors, tender chicken, fragrant garlic, and melty cheese, all enveloped around rotini pasta for the ultimate comfort food experience. Whether you need a quick dinner for busy nights, something special for guests, or just want to treat yourself to a hearty meal, this one-skillet wonder has you covered. Let’s get cooking!

Why You'll Love This Cheesy Cajun Garlic Chicken Rotini Skillet

One-pan meal keeps cleanup a breeze and saves time in the kitchen.
Perfect balance of spicy, garlicky, creamy, and cheesy flavors for irresistible bites.
Quick to make—just 35 minutes from start to finish!
Family-friendly and easily customizable for different taste preferences.
Packed with protein and comforting pasta for a satisfying dinner.

Cheesy Cajun Garlic Chicken Rotini Skillet Ingredients

2 medium boneless, skinless chicken breasts (about 1 lb), cut into 1-inch cubes
2 tablespoons Cajun seasoning
2 tablespoons olive oil, divided
4 cloves garlic, minced
1 small yellow onion, diced
1 red bell pepper, diced
1 green bell pepper, diced
2 cups rotini pasta (uncooked)
2 ½ cups low-sodium chicken broth
1 (14.5-oz) can diced tomatoes, drained
¾ cup heavy cream
1 ½ cups shredded mozzarella cheese
½ cup shredded sharp cheddar cheese
Salt and black pepper, to taste
Fresh chopped parsley, for garnish

Directions: How to Make Cheesy Cajun Garlic Chicken Rotini Skillet

Step 1: Prep and Season the Chicken

In a medium bowl, toss the cubed chicken with Cajun seasoning until evenly coated.

Step 2: Sear the Chicken

Heat 1 tablespoon olive oil in a large, deep skillet or sauté pan over medium-high heat. Add the seasoned chicken and sear for 3-4 minutes, stirring occasionally until golden but not fully cooked through. Remove chicken to a plate and set aside.

Step 3: Sauté the Vegetables

Reduce heat to medium. Add remaining tablespoon olive oil to the pan. Stir in garlic, onion, and both bell peppers. Sauté for 4-5 minutes, until vegetables are softened and fragrant.

Step 4: Cook the Pasta

Add the uncooked rotini, chicken broth, and drained diced tomatoes to the skillet. Stir well, scraping up any browned bits from the pan for extra flavor. Bring to a gentle boil, then reduce heat to maintain a simmer. Cover and cook for 10-12 minutes, stirring occasionally, until pasta is al dente and most of the liquid is absorbed.

Step 5: Finish with Chicken, Cream, and Cheese

Return chicken (and any juices) to the skillet. Pour in the heavy cream, mixing well. Simmer uncovered for another 3-4 minutes, until chicken is cooked through and sauce thickens slightly.
Sprinkle mozzarella and cheddar cheese evenly over the skillet. Cover and cook for 1-2 minutes, or until cheese is melted and gooey. Season with salt and pepper to taste.

Step 6: Serve and Enjoy!

Garnish with chopped parsley. Serve right from the skillet for a rustic, family-style meal!

Notes: Tips for the Best Cheesy Cajun Garlic Chicken Rotini Skillet

Don’t overcook the pasta: Check rotini a minute early for perfect al dente texture—see this guide to cooking pasta.
Spice level: Adjust the heat by using more or less Cajun seasoning. Make your own for complete control (see this recipe).
Dairy-free option: Substitute coconut cream and vegan cheeses for a dairy-free version.

Cheesy Cajun Garlic Chicken Rotini Skillet Variations

Sausage version: Swap chicken for sliced smoked sausage for a heartier, smoky twist.
Vegetarian variety: Omit chicken and use chickpeas or sautéed mushrooms for a veggie-packed meal.
Extra cheesy: Add an extra ½ cup of Monterey Jack or gouda for an ultra-cheesy skillet.

Required Equipment for Cheesy Cajun Garlic Chicken Rotini Skillet

Large, deep skillet or sauté pan with lid (12-inch preferred)
Chef’s knife and cutting board
Measuring cups and spoons
Wooden spoon or spatula

Storage Instructions

Let leftovers cool completely before transferring to an airtight container. Store in the refrigerator for up to 3 days. Reheat gently on the stove or in the microwave with a splash of broth or cream to revive the saucy consistency. While freezing is possible, the sauce may separate slightly upon thawing—best enjoyed fresh!

Pairings & Serving Ideas for Cheesy Cajun Garlic Chicken Rotini Skillet

Serve with a crisp green salad and crusty garlic bread.
Pair with roasted or steamed broccoli for added nutrition.
Enjoy with a glass of chilled Chardonnay or sparkling lemonade.

Pro Tips for Cheesy Cajun Garlic Chicken Rotini Skillet Success

Prep ahead: Dice veggies and measure ingredients before starting for smooth, stress-free cooking (see more cooking tips here).
Let cheese rest: Turn off the heat after adding cheese and let skillet stand for 3 minutes for maximum meltiness.
Boost flavor: For an extra depth, deglaze skillet with a splash of white wine before adding broth.

Cheesy Cajun Garlic Chicken Rotini Skillet FAQ

Can I use a different pasta shape? Yes—penne or fusilli work great, but you may need to adjust the cook time slightly.
Is this dish very spicy? It’s mildly spicy; reduce Cajun seasoning or use a mild blend for less heat.
Can I prepare this ahead? Absolutely—make up to 1 day in advance and reheat gently, adding a splash of broth or cream as needed.

Prep Time: 10 minutes
Cook Time: 25 minutes
Total Time: 35 minutes

Cheesy Cajun Garlic Chicken Rotini Skillet